Metal‐Cyclic Dinucleotide Nanomodulator‐Stimulated STING Signaling for Strengthened Radioimmunotherapy of Large Tumor (Small 41/2022)

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چکیده

Large Tumor Therapy In article number 2203227, Yanyu Huang, Liangping Luo, Zeyu Xiao, and co-workers report a localized radioimmunotherapeutic regimen by using X-ray irradiation metal-cyclic dinucleotide-containing nanomodulator for the treatment of large tumors. This combined paradigm amplifies STING signaling pathway elevating production 2′,3′-cGAMP activating both systematic anti-tumor immunity.

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ژورنال

عنوان ژورنال: Small

سال: 2022

ISSN: ['1613-6829', '1613-6810']

DOI: https://doi.org/10.1002/smll.202270219